Nanomedicine Vacancies & Studentships

Location: Cambridge, UK
Contract Type: Permanent
Application Close Date: 2021-11-30
Job Summary:
The Bioconjugation Group in Abzena Cambridge (UK) provides conjugation solutions to support partner antibody drug conjugate (ADC), oligonucleotide conjugate, PEGylation and other conjugate development programs. Using established conjugation chemistries and its next-generation conjugation platform ThioBridge® with access to a wide range of cargo’s, we design, synthesise and produce ADC candidates evaluated with support from the Design and Developability Groups for lead candidate selection.

Location: Sedgefield, County Durham, UK
Contract Type: Full-time - Permanent
Application Close Date: 2021-09-30
Job Summary:
CPI is seeking a Principal Scientist who holds excellent knowledge of global and UK challenges in Nanotherapeutic drug delivery systems and the role innovation can play in addressing those challenges. The Principal Scientist will focus on the creation and delivery of a range of projects to support the development of advanced drug products utilising Nanotherapeutic drug delivery systems for intracellular delivery, such as Lipid Nanoparticle Encapsulated RNA, with an emphasis on formulation development, optimisation and process development and scale-up. Working within the current Colloid Science team, the Principal Scientist will be responsible for developing and delivering CPI’s capability in Nanotherapeutic drug delivery systems, creating innovative solutions to problem- solving and continuously working within a dynamic and fast-moving environment. The Principal Scientist will be required to support key activities including: Contributing expert knowledge to inform CPI’s technology strategy and translating this into deliverable plans to achieve business objectives. Developing and retaining relevant knowledge and capability in nanotherapeutic drug delivery systems, to support the UK industry in the translation of state-of-the-art ideas into commercially viable processes and products. Working collaboratively with Business Development, Bid Development and technical colleagues, providing support relating to proposal/project development and direct customer engagement, seeking out and engaging in business development opportunities where appropriate. Ideally the Principal Scientist will have experience working within the pharma industry, specifically in supporting the commercialisation of advanced drug delivery systems, combined with strong technical leadership to drive and direct teams to successfully develop and deliver large innovation programmes. The Principal Scientist will also bring deep expertise in nanotherapeutic drug delivery scale-up and process development, strong problem-solving skills, and enthusiasm for leading programs across various stages of development. The Principal Scientist will have knowledge and potentially practical experience of current state-of-the-art laboratory equipment used for drug product development and can advise on and interpret data generated using such techniques. The Principal Scientist will be flexible, able to readily adapt to evolving project requirements, with the ability to simultaneously work on multiple projects. They will thrive working in a dynamic and collaborative environment, with effective influencing and communication skills.