Clinically approved nanomedicines and nanoformulations
| Nanomaterial | API | Brand name | Company | Approved |
| Polymer-protein conjugate | Adenosine Deaminase | Adagen® | Sigma-Tau Pharmaceuticals/ Enzon | 1990 (USA) |
| Micelle | Paclitaxel | Taxol® | Bristol Myres Squibb | 1992 (USA) |
| Polymer-protein conjugate | Asparaginase | Oncasper® | Enzon | 1994 (USA) |
| Liposome | Amphotericin B | Abelcet® | Sigma-Tau Pharmaceuticals | 1995 (USA) |
| Liposome | Doxorubicin | Caelyx® | Centocor Ortho Biotech/ Janssen Biotech | 1995 (USA), 1996 (EU) |
| Micelle | Docetaxel | Taxotere® | Sanofi-Aventis | 1995 (EU), 1996 (USA) |
| Polymeric drug | Glatiramer acetate | Copaxone® | Teva | 1996 (USA) |
| Liposome | Daunorubicin citrate | DaunoXome® | NeXstar Phamaceuticals/ Gilead | 1996 (USA) |
| SPION (diagnostic) | n/a | Endorem® | Guerbet/ Amag Pharmaceuticals | 1996 (USA) |
| SPION (diagnostic) | n/a | GastroMARK® | Guerbet/ Amag Pharmaceuticals | 1996 (USA/EU) |
| Liposome | Amphoteracin B | Ambisome® | Astellas Pharma/ Gilead | 1997 (USA) |
| Virosome | Vaccine | Inflexal® V | Berna Biotech/ Crucell | 1997 (USA) |
| Liposome | Cytarabine | Depocyt® | Pacira Pharms/ Sigma-Tau Pharmaceuticals | 1999 (USA), 2001 (EU) |
| Sodium ferric gluconate complex | Iron supplement | Ferrlecit® | Sanofi-Aventis | 1999 (USA) |
| Nanocrystal | Sirolimus | Rapamune® | Wyeth Pharm/ Pfizer | 1999 (USA), 2001 (EU) |
| Liposome | Doxorubicin | Myocet® | Sopherion Therapeutics/ Cephalon | 2000 (EU) |
| Polymer-protein conjugate | IFN-α2b | PEGINTRON® | Schering Plough | 2000 (EU), 2001 (USA) |
| Polymeric drug | Sevelamer HCl | Renagel® | Genzyme | 2000 (USA/EU) |
| Iron oxide glucose complex | Iron supplement | Venofer® | Fresenius/ Luipold | 2000 (USA) |
| Liposome | Verteporfin | Visudyne® | Novartis | 2000 (USA/EU) |
| Polymeric drug | Colesevelam HCl | Welchol® | Daiichi Sankyo | 2000 (USA) |
| SPION (diagnostic) | n/a | Resovist® | Bayer Schering Pharma | 2001 (EU) |
| Polymer-protein conjugate | PEGfilgrastim | Neulasta® | Amgen | 2002 (USA/EU) |
| Polymer-protein conjugate | IFN-α2a | PEGASYS® | Hoffmann-LaRoche | 2002 (USA/EU) |
| Polymer-protein conjugate | PEGvisomant | Somavert® | Pfizer | 2002 (EU), 2003 (USA) |
| Nanocrystal | Aprepitant | Emend® | Merck | 2003 (USA/EU) |
| Micelle | Estradiol hemihydrate | Estraorb™ | Novavax/ Graceway | 2003 (USA) |
| Liposome | Morphine sulphate | Depodur® | EKR Therapeutics | 2004 (USA) |
| Polymer-aptamer conjugate | siRNA | Macugen® | Eyetech | 2004 (USA), 2006 (EU) |
| Nanocrystal | Fenofibrate | Tricor® | Abbott | 2004 (USA) |
| Albumin nanoparticle | Paclitaxel | Abraxane® | Abraxis Bioscience/ Celgene Europe | 2005 (USA), 2008 (EU) |
| Nanocrystal | Megestrol acetate | Megace® EC | Par Pharmaceuticals | 2005 (USA) |
| Nanocrystal | Fenofibrate | Triglide® | SkyePharma/ First Horizon | 2005 (USA) |
| Polymer-protein conjugate | Epoetin β | Mircera® | Hoffmann-LaRoche | 2007 (USA/EU) |
| Polymer-protein conjugate | Anti-TNF-α | Cimzia® | Nektar | 2008 (USA), 2009 (EU) |
| SPION (diagnostic) | n/a | Feraheme® | Amag Pharmaceuticals/ Takeda | 2009 (USA) |
| Liposome | Mifamurtide | Mepact® | IDM Pharma | 2009 (EU) |
| Polymer-protein conjugate | Urate oxidase | Krystexxa® | Savient Pharmaceuticals | 2010 (USA) |
| Nanoemulsion | Dexpanthenol | Bepanthen® spray | Bayer | On market |
| Virosome | Vaccine | Epaxal® | Berna Biotech/ Crucell | On market |
| Virosome | Vaccine | Influvac® Plus | Solvay Pharma/ Abbott | On market |
| Albumin nanoparticle | Radiodiagnostic (99mTc) | Nanocoll® | GE Healthcare | On market |
| Gold nanoparticle (diagnostic) | n/a | Verigene® | Nanosphere | On market |
| Liposome | Vincristine sulphate | Marqibo® | Inex/ Enzon/ Thanlon Therapeutics | On market (2012) |